Archive for the 'Gastric Cancer' Category

Different esophageal cancer risks seen with gastric or duodenal ulcers

The risk of esophageal cancer differs in patients with gastric and duodenal ulcers, according to a report in the April issue of Gut.

Epidemiological evidence suggests that Helicobacter pylori infection is associated with a reduced risk of esophageal adenocarcinoma, the authors explain, but few studies have explored the risk of esophageal cancer according to histology in relation to peptic ulcer disease.

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High intakes of vitamin A, retinol, and carotenoids reduce gastric cancer risk

High intakes of vitamin A, retinol, and provitamin A carotenoids reduce the risk of gastric cancer, results of a study published in the February issue of the American Journal of Clinical Nutrition suggest.

“Vitamin A may influence gastric carcinogenesis through its essential role in controlling cell proliferation and differentiation,” Dr. Susanna C. Larsson, of Karolinska Institutet, Stockholm, Sweden, and colleagues write. “However, epidemiologic studies of vitamin A, retinol (preformed vitamin A), and provitamin A carotenoids in relation to the risk of gastric cancer have documented inconsistent results.”

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Pepsinogen, gastrin-17 biomarkers of atrophic gastritis and gastric cancer

Serum pepsinogen and gastrin-17 levels may be useful in screening for atrophic gastritis and gastric cancer, according to a report in the January issue of the Chinese Journal of Digestive Diseases.

“As serum biomarkers are useful to detect atrophic gastritis and the location of atrophic lesions (antrum or corpus), it is feasible to carry out the serum test for outpatients who may suffer from gastric cancer, in particular in high-risk areas of gastric cancer,” Dr. Shu Dong Xiao from Shanghai Jiaotong University, China.

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